Containment of artemisinin tolerant malaria parasites in South-East Asia (ARCE)
ARCE is a WHO-lead strategy for the containment of artemisinin resistant parasites in Southeast Asia, aiming to ultimately contribute to the elimination of falciparum malaria from the area. Samples collected as part of ARCE-lead studies of artesunate efficacy at sites in Myanmar, Laos and Viet Nam were contributed to the MalariaGEN P. falciparum Community Project for whole genome sequencing and subsequent analysis of genetic variation, population structure and signatures of selection. The genetic data is also being used in a replication genome-wide association study to validate and extend the outcomes of the ARC3 GWAS, with the hope of identifying molecular markers of artemisinin resistance.
Summary
- 234 Samples
- 3 Locations
Samples/Year
QC Pass
Samples that passed Whole-Genome Sequencing Quality Control (QC)
Resistance
Predicted resistance status for main antimalarial drug treatments from molecular markers
Locations
Binh Phuoc
Summary
Samples/Year
QC Pass
Samples that passed Whole-Genome Sequencing Quality Control (QC)
Resistance
Predicted resistance status for main antimalarial drug treatments from molecular markers
Savannakhet
Summary
Samples/Year
QC Pass
Samples that passed Whole-Genome Sequencing Quality Control (QC)
Resistance
Predicted resistance status for main antimalarial drug treatments from molecular markers
Tanintharyi
Summary
Samples/Year
QC Pass
Samples that passed Whole-Genome Sequencing Quality Control (QC)
Resistance
Predicted resistance status for main antimalarial drug treatments from molecular markers