Measuring in vitro drug sensitivity in Vietnam

Samples were collected in the southern province of Binh Phuoc, Vietnam, as part of a set of clinical studies initiated by Professor Tran Tinh Hien and Christiane Dolecek in 2009 to measure in vivo and in vitro drug sensitivity in this region. In collaboration with Maciej Boni, Professor Hien's research team also worked towards characterizing signatures of sulfadoxine/pyrimethamine and chloroquine resistance, and pfMDR copy number in these samples using the Illumina sequence and genotype data. Where samples were found to contain P. vivax data, for example due to mixed infection, this data was contributed to the P. vivax Genome Variation project.

Summary

Samples/Year

QC Pass

Samples that passed Whole-Genome Sequencing Quality Control (QC)

Resistance

Predicted resistance status for main antimalarial drug treatments from molecular markers

Locations

Binh Phuoc

Samples/Year

QC Pass

Samples that passed Whole-Genome Sequencing Quality Control (QC)

Resistance

Predicted resistance status for main antimalarial drug treatments from molecular markers