Malaria transmission dynamics in The Gambia: Defining the spatial and temporal spread of malaria at micro-level (village)

The overall objective of this study is to understand the determinants of malaria heterogeneity and the spatial and temporal spread of malaria infections. Alfred Amambua Ngwa and Umberto d’Alessandro will analyse P. falciparum specimens from 3 consecutive years in the country to describe infection, complexity and identify parasite genotypes adapting to current interventions and environmental changes in the population. The aim is to integrate high-throughput genomic technologies into detailed field epidemiology and entomology studies to increase our understanding of what drives the heterogeneities in host-parasite-vector interactions and ultimately transmission, providing the basis for the rational application of interventions and the development of evidence-based plans for elimination.

Summary

Samples/Year

QC Pass

Samples that passed Whole-Genome Sequencing Quality Control (QC)

Resistance

Predicted resistance status for main antimalarial drug treatments from molecular markers

Locations

Upper River

Samples/Year

QC Pass

Samples that passed Whole-Genome Sequencing Quality Control (QC)

Resistance

Predicted resistance status for main antimalarial drug treatments from molecular markers